Andrographolide Derivative AL-1 Ameliorates Dextran Sodium Sulfate-Induced Murine Colitis by Inhibiting NF-κB and MAPK Signaling Pathways

Trinitrobenzenesulfonic acid (TNBS) and dextran sodium sulfate (DSS) are commonly used to induce experimental murine ulcerative colitis (UC). Our recent study has demonstrated that a novel andrographolide derivative, AL-1, ameliorated TNBS-induced colitis in mice. However, the effect of AL-1 on DSS-...

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Vydáno v:Oxid Med Cell Longev
Hlavní autoři: Jing, Mei, Wang, Yuqiang, Xu, Lipeng
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800948/
https://ncbi.nlm.nih.gov/pubmed/31687082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/6138723
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