Blockade of IL-17A/IL-17R Pathway Protected Mice from Sepsis-Associated Encephalopathy by Inhibition of Microglia Activation

Sepsis-associated encephalopathy (SAE) is a poorly understood condition that leads to long-term cognitive impairment and increased mortality in survivors. Recent research revealed that IL-17A/IL-17R might serve as a checkpoint in microglia-mediated neuroinflammation. The present study was designed t...

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Publicado en:Mediators Inflamm
Autores principales: Ye, Bo, Tao, Tianzhu, Zhao, Andong, Wen, Liyuan, He, Xiaofei, Liu, Yi, Fu, Qiang, Mi, Weidong, Lou, Jingsheng
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800921/
https://ncbi.nlm.nih.gov/pubmed/31686986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/8461725
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