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Impact of SLCO1B3 Polymorphisms on Clinical Outcomes in Lung Allograft Recipients Receiving Mycophenolic Acid

Single nucleotide polymorphisms (SNPs) in genes involved in mycophenolic acid (MPA) metabolism have been shown to contribute to variable MPA exposure, but their clinical effects are unclear. We aimed to determine if SNPs in key genes in MPA metabolism affect outcomes after lung transplantation. We p...

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Detalhes bibliográficos
Publicado no:Pharmacogenomics J
Main Authors: Tague, Laneshia K., Byers, Derek E, Hachem, Ramsey, Kreisel, Daniel, Krupnick, Alexander S., Kulkarni, Hrishikesh S., Chen, Catherine, Huang, Howard J, Gelman, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800829/
https://ncbi.nlm.nih.gov/pubmed/30992538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41397-019-0086-0
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