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Quantifying the dynamics of hematopoiesis by in vivo IdU pulse-chase, mass cytometry and mathematical modeling

We present a new method to directly quantify the dynamics of differentiation of multiple cellular subsets in unperturbed mice. We combine a pulse-chase protocol of IdU injections with subsequent analysis by mass cytometry (CyTOF), and mathematical modeling of the IdU dynamics. Measurements by CyTOF...

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Dettagli Bibliografici
Pubblicato in:Cytometry A
Autori principali: Erez, Amir, Mukherjee, Ratnadeep, Altan-Bonnet, Grégoire
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800754/
https://ncbi.nlm.nih.gov/pubmed/31150166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.a.23799
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