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Human β-defensin-3 participates in intra-amniotic host defense in women with labor at term, spontaneous preterm labor and intact membranes, and preterm prelabor rupture of membranes

OBJECTIVE: Human β-defensin-3 (HBD-3) has a broad spectrum of anti-microbial activity and, therefore, plays a central role in host defense mechanisms against infection. Herein, we determined whether HBD-3 was a physiological constituent of amniotic fluid during mid-trimester and at term, and whether...

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Bibliographic Details
Published in:J Matern Fetal Neonatal Med
Main Authors: Para, Robert, Romero, Roberto, Miller, Derek, Panaitescu, Bogdan, Varrey, Aneesha, Chaiworapongsa, Tinnakorn, Hassan, Sonia S., Hsu, Chaur-Dong, Gomez-Lopez, Nardhy
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800590/
https://ncbi.nlm.nih.gov/pubmed/30999788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14767058.2019.1597047
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