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Pairing interactions between nucleobases and ligands in aptamer:ligand complexes of riboswitches: crystal structure analysis, classification, optimal structures, and accurate interaction energies

In the present work, 67 crystal structures of the aptamer domains of RNA riboswitches are chosen for analysis of the structure and strength of hydrogen bonding (pairing) interactions between nucleobases constituting the aptamer binding pockets and the bound ligands. A total of 80 unique base:ligand...

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Bibliografiske detaljer
Udgivet i:RNA
Main Authors: Seelam, Preethi P., Mitra, Abhijit, Sharma, Purshotam
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800475/
https://ncbi.nlm.nih.gov/pubmed/31315914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.071530.119
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