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Empirical measures of mutational effects define neutral models of regulatory evolution in Saccharomyces cerevisiae

Understanding how phenotypes evolve requires disentangling the effects of mutation generating new variation from the effects of selection filtering it. Tests for selection frequently assume that mutation introduces phenotypic variation symmetrically around the population mean, yet few studies have t...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hodgins-Davis, Andrea, Duveau, Fabien, Walker, Elizabeth A., Wittkopp, Patricia J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800378/
https://ncbi.nlm.nih.gov/pubmed/31570626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902823116
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