In Vitro Modeling of the Bipolar Disorder and Schizophrenia Using Patient-Derived Induced Pluripotent Stem Cells with Copy Number Variations of PCDH15 and RELN

Bipolar disorder (BP) and schizophrenia (SCZ) are major psychiatric disorders, but the molecular mechanisms underlying the complicated pathologies of these disorders remain unclear. It is difficult to establish adequate in vitro models for pathological analysis because of the heterogeneity of these...

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Detalhes bibliográficos
Publicado no:eNeuro
Main Authors: Ishii, Takaya, Ishikawa, Mitsuru, Fujimori, Koki, Maeda, Takuji, Kushima, Itaru, Arioka, Yuko, Mori, Daisuke, Nakatake, Yuhki, Yamagata, Bun, Nio, Shintaro, Kato, Takahiro A., Yang, Nan, Wernig, Marius, Kanba, Shigenobu, Mimura, Masaru, Ozaki, Norio, Okano, Hideyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2019
Assuntos:
New Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800292/
https://ncbi.nlm.nih.gov/pubmed/31540999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0403-18.2019
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