p53-Pirh2 Complex Promotes Twist1 Degradation and Inhibits EMT

Epithelial-mesenchymal transition (EMT) is a critical process involved in cancer metastasis and chemo-resistance. Twist1 is a key EMT-inducing transcription factor, which is upregulated in multiple types of cancers and has been shown to promote tumor cell invasiveness and support tumor progression....

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Опубликовано в: :Mol Cancer Res
Главные авторы: Yang-Hartwich, Yang, Tedja, Roslyn, Roberts, Cai, Goodner-Bingham, Jamie, Cardenas, Carlos, Gurea, Marta, Sumi, Natalia J., Alvero, Ayesha B., Glackin, Carlotta A, Mor, Gil
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800184/
https://ncbi.nlm.nih.gov/pubmed/30131448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-0238
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