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Noncoding RNA genes in cancer pathogenesis
By using chronic lymphocytic leukemia as target for discovery in cancer pathogenesis we discovered that the great majority of CLLs (75-85%) carry a deletion of miR-15a and miR-16-1 at 13q14. We also discovered that miR-15/16 are negative regulators of the BCL2 oncogene. Thus the loss of the two nega...
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| Izdano u: | Adv Biol Regul |
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| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6800108/ https://ncbi.nlm.nih.gov/pubmed/30611710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbior.2018.12.002 |
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