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Toward point-of-care assessment of patient response: a portable tool for rapidly assessing cancer drug efficacy using multifrequency impedance cytometry and supervised machine learning

We present a novel method to rapidly assess drug efficacy in targeted cancer therapy, where antineoplastic agents are conjugated to antibodies targeting surface markers on tumor cells. We have fabricated and characterized a device capable of rapidly assessing tumor cell sensitivity to drugs using mu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Microsyst Nanoeng
Hauptverfasser: Ahuja, Karan, Rather, Gulam M., Lin, Zhongtian, Sui, Jianye, Xie, Pengfei, Le, Tuan, Bertino, Joseph R., Javanmard, Mehdi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6799891/
https://ncbi.nlm.nih.gov/pubmed/31645995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41378-019-0073-2
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