2213 Tumor suppressors p53 and ARF control oncogenic potential of triple-negative breast cancer cells by regulating RNA editing enzyme ADAR1

OBJECTIVES/SPECIFIC AIMS: Triple-negative breast cancer (TNBC) accounts for one-fifth of the breast cancer patient population. The heterogeneous nature of TNBC and lack of options for targeted therapy make its treatment a constant adventure. The deficiency of tumor suppressors p53 and ARF is one of...

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Detalhes bibliográficos
Publicado no:J Clin Transl Sci
Main Authors: Kung, Che-Pei, Bross, Emily A., Kuzmicki, Catherine E., Benjamin, Michael, Maggi, Leonard B., Weber, Jason D.
Formato: Artigo
Idioma:Inglês
Publicado em: Cambridge University Press 2018
Assuntos:
Basic/Translational Science/Team Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6799729/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2018.143
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