2081: Phenotypic characterization of the CD4+ T-cell response during anti-CTLA4 therapy with ipilimumab in melanoma patients

OBJECTIVES/SPECIFIC AIMS: To characterize the CD4+ T-cell response during CTLA-4 blockade immunotherapy with ipilimumab in patients with metastatic melanoma by correlating cytokine profiles with phenotypic changes in the intratumoral lymphocyte compartment of tumor biopsies obtained before and after...

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發表在:J Clin Transl Sci
Main Authors: Sherani, Farha, Moogk, Duane, Bapodra, Anuj, Malecek, Karolina, Moran, Una, Lee, Yesung, Osman, Iman, Krogsgaard, Michelle
格式: Artigo
語言:Inglês
出版: Cambridge University Press 2018
主題:
Mechanistic Basic to Clinical
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6799028/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2017.199
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