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2467 PRMT5 is a master epigenetic regulator to promote repair of radiation-induced DNA damage
OBJECTIVES/SPECIFIC AIMS: We recently reported that PRMT5 epigenetically activates androgen receptor (AR) in prostate cancer cells. Because targeting AR signaling through androgen deprivation therapy is clinically used as a radiosensitization approach to treat high-risk prostate cancer, our finding...
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| Publicado no: | J Clin Transl Sci |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cambridge University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6798993/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2018.109 |
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