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2304: Identifying optimal multiple sclerosis (MS)-specific atrophy markers as primary endpoint for Phase II s in progressive MS

OBJECTIVES/SPECIFIC AIMS: To identify brain regions with the highest and least variable rate of multiple sclerosis (MS)-specific atrophy using an agnostic approach, and to perform simulation-based sample size calculations for Phase II s using these regions as primary endpoint. METHODS/STUDY POPULATI...

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Detalhes bibliográficos
Publicado no:J Clin Transl Sci
Main Authors: Azevedo, Christina, Cen, Steven, Zheng, Ling, Amirhossein Jaberzadeh, Pelletier
Formato: Artigo
Idioma:Inglês
Publicado em: Cambridge University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798701/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2017.127
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