Quantitative nuclear histomorphometric features are predictive of Oncotype DX risk categories in ductal carcinoma in situ: preliminary findings

BACKGROUND: Oncotype DX (ODx) is a 12-gene assay assessing the recurrence risk (high, intermediate, and low) of ductal carcinoma in situ (pre-invasive breast cancer), which guides clinicians regarding prescription of radiotherapy. However, ODx is expensive, time-consuming, and tissue-destructive. In...

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Publicado en:Breast Cancer Res
Autores principales: Li, Haojia, Whitney, Jon, Bera, Kaustav, Gilmore, Hannah, Thorat, Mangesh A., Badve, Sunil, Madabhushi, Anant
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798488/
https://ncbi.nlm.nih.gov/pubmed/31623652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-019-1200-6
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