DeepImpute: an accurate, fast, and scalable deep neural network method to impute single-cell RNA-seq data

Single-cell RNA sequencing (scRNA-seq) offers new opportunities to study gene expression of tens of thousands of single cells simultaneously. We present DeepImpute, a deep neural network-based imputation algorithm that uses dropout layers and loss functions to learn patterns in the data, allowing fo...

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Detalles Bibliográficos
Publicado en:Genome Biol
Main Authors: Arisdakessian, Cédric, Poirion, Olivier, Yunits, Breck, Zhu, Xun, Garmire, Lana X.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
Assuntos:
Method
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798445/
https://ncbi.nlm.nih.gov/pubmed/31627739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1837-6
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