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Alteration in TET1 as potential biomarker for immune checkpoint blockade in multiple cancers

BACKGROUND: Immune checkpoint inhibitors (ICIs) have achieved impressive success in different cancer types, yet responses vary and predictive biomarkers are urgently needed. Growing evidence points to a link between DNA methylation and anti-tumor immunity, while clinical data on the association of g...

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Détails bibliographiques
Publié dans:J Immunother Cancer
Auteurs principaux: Wu, Hao-Xiang, Chen, Yan-Xing, Wang, Zi-Xian, Zhao, Qi, He, Ming-Ming, Wang, Ying-Nan, Wang, Feng, Xu, Rui-Hua
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798429/
https://ncbi.nlm.nih.gov/pubmed/31623662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0737-3
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