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Evaluation of Cytotoxicity of Perfluorocarbons for Intraocular Use by Cytotoxicity Test In Vitro in Cell Lines and Human Donor Retina Ex Vivo

PURPOSE: To validate the cytotoxicity test of perfluorocarbon liquids (PFCLs) for intraocular use according to the ISO 10993-5 standard. METHODS: BALB/3T3, ARPE-19 cell lines, and 3-mm human retina ex vivo samples were cultured in 96-well plates. Contact areas of 22%, 59%, and 83% and 2.5-, 12-, and...

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Détails bibliographiques
Publié dans:Transl Vis Sci Technol
Auteurs principaux: Romano, Mario R., Ferrara, Mariantonia, Gatto, Claudio, Ferrari, Barbara, Giurgola, Laura, D'Amato Tóthová, Jana
Format: Artigo
Langue:Inglês
Publié: The Association for Research in Vision and Ophthalmology 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798311/
https://ncbi.nlm.nih.gov/pubmed/31637104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/tvst.8.5.24
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