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Translational Approaches Targeting Ceramide Generation From Sphingomyelin in T Cells to Modulate Immunity in Humans

In T cells, as in all other cells of the body, sphingolipids form important structural components of membranes. Due to metabolic modifications, sphingolipids additionally play an active part in the signaling of cell surface receptors of T cells like the T cell receptor or the co-stimulatory molecule...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Hollmann, Claudia, Wiese, Teresa, Dennstädt, Fabio, Fink, Julian, Schneider-Schaulies, Jürgen, Beyersdorf, Niklas
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798155/
https://ncbi.nlm.nih.gov/pubmed/31681273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02363
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