Translational Approaches Targeting Ceramide Generation From Sphingomyelin in T Cells to Modulate Immunity in Humans

In T cells, as in all other cells of the body, sphingolipids form important structural components of membranes. Due to metabolic modifications, sphingolipids additionally play an active part in the signaling of cell surface receptors of T cells like the T cell receptor or the co-stimulatory molecule...

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Vydáno v:Front Immunol
Hlavní autoři: Hollmann, Claudia, Wiese, Teresa, Dennstädt, Fabio, Fink, Julian, Schneider-Schaulies, Jürgen, Beyersdorf, Niklas
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798155/
https://ncbi.nlm.nih.gov/pubmed/31681273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02363
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