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Zika Virus Infection Induces DNA Damage Response in Human Neural Progenitors That Enhances Viral Replication

Zika virus (ZIKV) infection attenuates the growth of human neural progenitor cells (hNPCs). As these hNPCs generate the cortical neurons during early brain development, the ZIKV-mediated growth retardation potentially contributes to the neurodevelopmental defects of the congenital Zika syndrome. Her...

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Publicado en:J Virol
Main Authors: Hammack, Christy, Ogden, Sarah C., Madden, Joseph C., Medina, Angelica, Xu, Chongchong, Phillips, Ernest, Son, Yuna, Cone, Allaura, Giovinazzi, Serena, Didier, Ruth A., Gilbert, David M., Song, Hongjun, Ming, Guoli, Wen, Zhexing, Brinton, Margo A., Gunjan, Akash, Tang, Hengli
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798117/
https://ncbi.nlm.nih.gov/pubmed/31375586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00638-19
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