Curcumin Blocks Cytotoxicity of Enteroaggregative and Enteropathogenic Escherichia coli by Blocking Pet and EspC Proteolytic Release From Bacterial Outer Membrane

Pet and EspC are toxins secreted by enteroaggregative (EAEC) and enteropathogenic (EPEC) diarrheagenic Escherichia coli pathotypes, respectively. Both toxins are members of the Serine Protease Autotransporters of Enterobacteriaceae (SPATEs) family. Pet and EspC are important virulence factors that p...

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Publicado en:Front Cell Infect Microbiol
Autores principales: Sanchez-Villamil, Javier I., Navarro-Garcia, Fernando, Castillo-Romero, Araceli, Gutierrez-Gutierrez, Filiberto, Tapia, Daniel, Tapia-Pastrana, Gabriela
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798032/
https://ncbi.nlm.nih.gov/pubmed/31681620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00334
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