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Activation of TGR5 alleviates inflammation in rheumatoid arthritis peripheral blood mononuclear cells and in mice with collagen II-induced arthritis

Rheumatoid arthritis (RA) is characterized by chronic inflammatory synovitis resulting in progressive joint destruction. Persistent synovial inflammation is induced by activation of various inflammatory cells. G-protein-coupled bile acid receptor 1 (TGR5) is a G-protein-coupled receptor activated by...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Li, Zhe-Yong, Zhou, Jing-Jing, Luo, Chun-Lei, Zhang, Le-Meng
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797944/
https://ncbi.nlm.nih.gov/pubmed/31702035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.10711
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