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PTEN modulates neurites outgrowth and neuron apoptosis involving the PI3K/Akt/mTOR signaling pathway

The present study aimed to explore the role of the PTEN/Akt/mTOR signaling pathway in the neurite outgrowth and apoptosis of cortical neurons. Cortical neurons were seeded on or adjacent to chondroitin sulfate proteoglycans. The length, number and crossing behavior of the neurites were calculated. I...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Liu, Shen, Jia, Jun, Zhou, Hengxing, Zhang, Chi, Liu, Lu, Liu, Jun, Lu, Lu, Li, Xueying, Kang, Yi, Lou, Yongfu, Cai, Zhiwei, Ren, Yiming, Kong, Xiaohong, Feng, Shiqing
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797942/
https://ncbi.nlm.nih.gov/pubmed/31702028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.10670
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