PTEN modulates neurites outgrowth and neuron apoptosis involving the PI3K/Akt/mTOR signaling pathway

The present study aimed to explore the role of the PTEN/Akt/mTOR signaling pathway in the neurite outgrowth and apoptosis of cortical neurons. Cortical neurons were seeded on or adjacent to chondroitin sulfate proteoglycans. The length, number and crossing behavior of the neurites were calculated. I...

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Veröffentlicht in:Mol Med Rep
Hauptverfasser: Liu, Shen, Jia, Jun, Zhou, Hengxing, Zhang, Chi, Liu, Lu, Liu, Jun, Lu, Lu, Li, Xueying, Kang, Yi, Lou, Yongfu, Cai, Zhiwei, Ren, Yiming, Kong, Xiaohong, Feng, Shiqing
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2019
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797942/
https://ncbi.nlm.nih.gov/pubmed/31702028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.10670
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