Dendritic Cells Generated From Mops condylurus, a Likely Filovirus Reservoir Host, Are Susceptible to and Activated by Zaire Ebolavirus Infection

Ebola virus infection of human dendritic cells (DCs) induces atypical adaptive immune responses and thereby exacerbates Ebola virus disease (EVD). Human DCs, infected with Ebola virus aberrantly express low levels of the DC activation markers CD80, CD86, and MHC class II. The T cell responses ensuin...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Edenborough, Kathryn M., Bokelmann, Marcel, Lander, Angelika, Couacy-Hymann, Emmanuel, Lechner, Johanna, Drechsel, Oliver, Renard, Bernhard Y., Radonić, Aleksandar, Feldmann, Heinz, Kurth, Andreas, Prescott, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797855/
https://ncbi.nlm.nih.gov/pubmed/31681302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02414
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