Single-cell transcriptomics of human T cells reveals tissue and activation signatures in health and disease

Human T cells coordinate adaptive immunity in diverse anatomic compartments through production of cytokines and effector molecules, but it is unclear how tissue site influences T cell persistence and function. Here, we use single cell RNA-sequencing (scRNA-seq) to define the heterogeneity of human T...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Szabo, Peter A., Levitin, Hanna Mendes, Miron, Michelle, Snyder, Mark E., Senda, Takashi, Yuan, Jinzhou, Cheng, Yim Ling, Bush, Erin C., Dogra, Pranay, Thapa, Puspa, Farber, Donna L., Sims, Peter A.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797728/
https://ncbi.nlm.nih.gov/pubmed/31624246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12464-3
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