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Identification and Validation of a Novel Biologics Target in Triple Negative Breast Cancer
The goal of this study was to identify a novel target for antibody-drug conjugate (ADC) development in triple negative breast cancer (TNBC), which has limited treatment options, using gene expression datasets and in vitro siRNA/CRISPR and in vivo functional assays. We analyzed 4467 breast cancers an...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6797726/ https://ncbi.nlm.nih.gov/pubmed/31624295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51453-w |
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