Pathologic complete response and outcomes by intrinsic subtypes in NSABP B-41, a randomized neoadjuvant trial of chemotherapy with trastuzumab, lapatinib, or the combination

PURPOSE: NSABP B-41, a phase three randomized trial, evaluated neoadjuvant lapatinib, trastuzumab, or the combination with chemotherapy in patients with HER2-positive operable breast cancer. Though no significant difference in pathologic complete response (pCR) was found among the three arms, pCR wa...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res Treat
Main Authors: Swain, Sandra M., Tang, Gong, Lucas, Peter C., Robidoux, André, Goerlitz, David, Harris, Brent T., Bandos, Hanna, Geyer, Charles E., Rastogi, Priya, Mamounas, Eleftherios P., Wolmark, Norman
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2019
Assuntos:
Clinical Trial
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797698/
https://ncbi.nlm.nih.gov/pubmed/31428908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-019-05398-3
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