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Potent anti‐angiogenesis and anti‐tumour activity of pegaptanib‐loaded tetrahedral DNA nanostructure

OBJECTIVES: Pegaptanib might be a promising anti‐tumour drug targeting VEGF to inhibit tumour vascular endothelial cell proliferation. However, the poor biostability limited its application. In this study, we took tetrahedron DNA nanostructures (TDNs) as drug nanocarrier for pegaptanib to explore th...

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Detaylı Bibliyografya
Yayımlandı:Cell Prolif
Asıl Yazarlar: Xie, Xueping, Zhang, Yuxin, Ma, Wenjuan, Shao, Xiaoru, Zhan, Yuxi, Mao, Chenchen, Zhu, Bofeng, Zhou, Yi, Zhao, Hu, Cai, Xiaoxiao
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797503/
https://ncbi.nlm.nih.gov/pubmed/31364793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12662
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