Metastatic niche labelling reveals tissue parenchyma stem cell features

To date, a direct investigation of the early cellular changes induced by metastatic cells within the surrounding tissue is difficult to achieve. We present the strategy whereby metastatic cancer cells release a cell-penetrating fluorescent protein taken up by neighbouring cells, allowing spatial ide...

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Published in:Nature
Main Authors: Ombrato, Luigi, Nolan, Emma, Kurelac, Ivana, Mavousian, Antranik, Bridgeman, Victoria, Heinze, Ivonne, Chakravarty, Probir, Horswell, Stuart, Gonzalez-Gualda, Estela, Matacchione, Giulia, Weston, Anne, Kirkpatrick, Joanna, Husain, Ehab, Speirs, Valerie, Collinson, Lucy, Ori, Alessandro, Lee, Joo-Hyeon, Malanchi, Ilaria
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797499/
https://ncbi.nlm.nih.gov/pubmed/31462798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1487-6
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