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Induced cardiomyocyte maturation: Cardiac transcription factors are necessary but not sufficient

The process by which fibroblasts are directly reprogrammed into cardiomyocytes involves two stages; initiation and maturation. Initiation represents the initial expression of factors that induce fibroblasts to transdifferentiate into cardiomyocytes. Following initiation, the cell undergoes a period...

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Publicat a:PLoS One
Autors principals: Dal-Pra, Sophie, Hodgkinson, Conrad P., Dzau, Victor J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797484/
https://ncbi.nlm.nih.gov/pubmed/31622977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0223842
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