First identification of the benzimidazole resistance-associated F200Y SNP in the beta-tubulin gene in Ascaris lumbricoides

The main control strategy for Ascaris lumbricoides is mass drug administration (especially with benzimidazoles), which can select strains of parasites resistant to treatment. Mutations in the beta-tubulin isotype-1 gene at codons 167, 198 and 200 have been linked to benzimidazole resistance in sever...

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Udgivet i:PLoS One
Main Authors: Furtado, Luis Fernando Viana, Medeiros, Celi da Silva, Zuccherato, Luciana Werneck, Alves, William Pereira, de Oliveira, Valéria Nayara Gomes Mendes, da Silva, Vivian Jordania, Miranda, Guilherme Silva, Fujiwara, Ricardo Toshio, Rabelo, Élida Mara Leite
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797262/
https://ncbi.nlm.nih.gov/pubmed/31622428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224108
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