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Switching to bedaquiline for treatment of rifampicin-resistant tuberculosis in South Africa: A retrospective cohort analysis

South Africa led the world with guidelines on bedaquiline (BDQ) use as a single drug substitution to manage rifampin resistant tuberculosis regimen toxicity. We examined reasons for giving BDQ in a retrospective cohort: >75% of patients were switched to BDQ for toxicity (ototoxicity or renal dysf...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bouton, Tara C., de Vos, Margaretha, Ragan, Elizabeth J., White, Laura F., Van Zyl, Leonie, Theron, Danie, Horsburgh, C. Robert, Warren, Robin M., Jacobson, Karen R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797261/
https://ncbi.nlm.nih.gov/pubmed/31622366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0223308
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