Analysis of a fully infectious bio-orthogonally modified human virus reveals novel features of virus cell entry

We report the analysis of a complex enveloped human virus, herpes simplex virus (HSV), assembled after in vivo incorporation of bio-orthogonal methionine analogues homopropargylglycine (HPG) or azidohomoalanine (AHA). We optimised protocols for the production of virions incorporating AHA (termed HSV...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Serwa, Remigiusz A., Sekine, Eiki, Brown, Jonathan, Teo, Su Hui Catherine, Tate, Edward W., O’Hare, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797222/
https://ncbi.nlm.nih.gov/pubmed/31589653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007956
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