An integrated epigenome and transcriptome analysis identifies PAX2 as a master regulator of drug resistance in high grade pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is notoriously difficult to treat due to its aggressive, ever resilient nature. A major drawback lies in its tumor grade; a phenomenon observed across various carcinomas, where highly differentiated and undifferentiated tumor grades, termed as low and high gra...

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Bibliographic Details
Published in:PLoS One
Main Authors: Aier, Imlimaong, Semwal, Rahul, Dhara, Aiindrila, Sen, Nirmalya, Varadwaj, Pritish Kumar
Format: Artigo
Language:Inglês
Published: Public Library of Science 2019
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797122/
https://ncbi.nlm.nih.gov/pubmed/31622355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0223554
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