Hierarchical activation of compartmentalized pools of AMPK depends on severity of nutrient or energy stress

AMPK, a master regulator of metabolic homeostasis, is activated by both AMP-dependent and AMP-independent mechanisms. The conditions under which these different mechanisms operate, and their biological implications are unclear. Here, we show that, depending on the degree of elevation of cellular AMP...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Zong, Yue, Zhang, Chen-Song, Li, Mengqi, Wang, Wen, Wang, Zhichao, Hawley, Simon A., Ma, Teng, Feng, Jin-Wei, Tian, Xiao, Qi, Qu, Wu, Yu-Qing, Zhang, Cixiong, Ye, Zhiyun, Lin, Shu-Yong, Piao, Hai-Long, Hardie, D. Grahame, Lin, Sheng-Cai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796943/
https://ncbi.nlm.nih.gov/pubmed/30948787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-019-0163-6
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados