The Discovery of RNA Aptamers that Selectively Bind Glioblastoma Stem Cells

Glioblastoma (GBM) is the most aggressive primary brain tumor in adults. Despite progress in surgical and medical neuro-oncology, prognosis for GBM patients remains dismal, with a median survival of only 14–15 months. The modest benefit of conventional therapies is due to the presence of GBM stem ce...

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Veröffentlicht in:Mol Ther Nucleic Acids
Hauptverfasser: Affinito, Alessandra, Quintavalle, Cristina, Esposito, Carla Lucia, Roscigno, Giuseppina, Vilardo, Claudia, Nuzzo, Silvia, Ricci-Vitiani, Lucia, De Luca, Gabriele, Pallini, Roberto, Kichkailo, Anna S., Lapin, Ivan N., de Franciscis, Vittorio, Condorelli, Gerolama
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796606/
https://ncbi.nlm.nih.gov/pubmed/31541799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.08.015
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