Molecular mechanisms underlying mifepristone's agonistic action on ovarian cancer progression

BACKGROUND: Recent clinical trials on ovarian cancer with mifepristone (MF) have failed, despite in vitro findings on its strong progesterone (P4) antagonist function. METHODS: Ovarian cancer human and murine cell lines, cultured high-grade human primary epithelial ovarian cancer (HG-hOEC) cells and...

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發表在:EBioMedicine
Main Authors: Ponikwicka-Tyszko, Donata, Chrusciel, Marcin, Stelmaszewska, Joanna, Bernaczyk, Piotr, Chrusciel, Paulina, Sztachelska, Maria, Scheinin, Mika, Bidzinski, Mariusz, Szamatowicz, Jacek, Huhtaniemi, Ilpo T., Wolczynski, Slawomir, Rahman, Nafis A.
格式: Artigo
語言:Inglês
出版: Elsevier 2019
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Research paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796594/
https://ncbi.nlm.nih.gov/pubmed/31466918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.08.035
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