TGF-β-induced transgelin promotes bladder cancer metastasis by regulating epithelial-mesenchymal transition and invadopodia formation

BACKGROUND: Metastatic bladder cancer (BLCA) is a lethal disease with an unmet need for study. Transgelin (TAGLN) is an actin-binding protein that affects the dynamics of the actin cytoskeleton indicating its robust potential as a metastasis initiator. Here, we sought to explore the expression patte...

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Publicado en:EBioMedicine
Autores principales: Chen, Zhicong, He, Shiming, Zhan, Yonghao, He, Anbang, Fang, Dong, Gong, Yanqing, Li, Xuesong, Zhou, Liqun
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796540/
https://ncbi.nlm.nih.gov/pubmed/31420300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.08.012
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