NMDA receptor modulation of glutamate release in activated neutrophils

BACKGROUND: Neutrophil depletion improves neurologic outcomes in experimental sepsis/brain injury. We hypothesized that neutrophils may exacerbate neuronal injury through the release of neurotoxic quantities of the neurotransmitter glutamate. METHODS: Real-time glutamate release by primary human neu...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: del Arroyo, Ana Gutierrez, Hadjihambi, Anna, Sanchez, Jenifer, Turovsky, Egor, Kasymov, Vitaly, Cain, David, Nightingale, Tom D., Lambden, Simon, Grant, Seth G.N., Gourine, Alexander V., Ackland, Gareth L.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796524/
https://ncbi.nlm.nih.gov/pubmed/31401196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.08.004
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