Biodistribution, shedding, and transmissibility of the oncolytic virus talimogene laherparepvec in patients with melanoma

BACKGROUND: Talimogene laherparepvec (T-VEC) is an intralesionally delivered, modified herpes simplex virus type-1 oncolytic immunotherapy. The biodistribution, shedding, and potential transmission of T-VEC was systematically evaluated during and after completion of therapy in adults with advanced m...

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Publicat a:EBioMedicine
Autors principals: Andtbacka, Robert H.I., Amatruda, Thomas, Nemunaitis, John, Zager, Jonathan S., Walker, John, Chesney, Jason A., Liu, Kate, Hsu, Cheng-Pang, Pickett, Cheryl A., Mehnert, Janice M.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Research paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796514/
https://ncbi.nlm.nih.gov/pubmed/31409575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.07.066
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