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Astragaloside IV regulates NF-κB-mediated cellular senescence and apoptosis of hepatic stellate cells to suppress PDGF-BB-induced activation

Activated hepatic stellate cells (HSCs) are the principal effectors during hepatic fibrosis, which is characterized by the accumulation of extracellular matrix. Therefore, present therapies and investigations into hepatic fibrosis mainly focus on the suppression of activated HSCs. Astragaloside IV (...

詳細記述

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書誌詳細
出版年:Exp Ther Med
主要な著者: Chen, Zhiwei, Yao, Ling, Liu, Yuanyuan, Pan, Zheng, Peng, Shuang, Wan, Guoguo, Cheng, Junxiong, Wang, Jianwei, Cao, Wenfu
フォーマット: Artigo
言語:Inglês
出版事項: D.A. Spandidos 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796432/
https://ncbi.nlm.nih.gov/pubmed/31641375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2019.8047
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