Perinatal Bisphenol A Exposure and Reprogramming of Imprinted Gene Expression in the Adult Mouse Brain

Genomic imprinting, a phenomenon by which genes are expressed in a monoallelic, parent-of-origin-dependent fashion, is critical for normal brain development. Expression of imprinted genes is regulated via epigenetic mechanisms, including DNA methylation (5-methylcytosine, 5mC), and disruptions in im...

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Publicat a:Front Genet
Autors principals: Malloy, Maureen A., Kochmanski, Joseph J., Jones, Tamara R., Colacino, Justin A., Goodrich, Jaclyn M., Dolinoy, Dana C., Svoboda, Laurie K.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Genetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796247/
https://ncbi.nlm.nih.gov/pubmed/31649729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00951
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