P11.09 Pan-RTK inhibition of sLRIG1 mediates AXL downregulation in Glioblastoma

INTRODUCTION: Aberrant regulation of receptor tyrosine kinase (RTK) activity is characteristic of Glioblastoma (GBM). However, RTK-based targeted therapies have been largely unsuccessful in GBM patients, partially due to the complexity and redundance of RTK signaling. LRIG1 (Leucine-rich Repeats and...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Neirinckx, V, Hau, A, Schuster, A, Fritah, S, Chevigné, A, Schmidt, M H H, Niclou, S P
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
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Poster Presentations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796174/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz126.155
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