Differential protein expression of DARPP-32 versus Calcineurin in the prefrontal cortex and nucleus accumbens in schizophrenia and bipolar disorder

Dopamine- and cAMP-regulated phosphoprotein of molecular weight 32 kDa (DARPP-32) integrates dopaminergic signaling into that of several other neurotransmitters. Calcineurin (CaN), located downstream of dopaminergic pathways, inactivates DARPP-32 by dephosphorylation. Despite several studies have ex...

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Publicat a:Sci Rep
Autors principals: Kunii, Yasuto, Hino, Mizuki, Matsumoto, Junya, Nagaoka, Atsuko, Nawa, Hiroyuki, Kakita, Akiyoshi, Akatsu, Hiroyasu, Hashizume, Yoshio, Yabe, Hirooki
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796065/
https://ncbi.nlm.nih.gov/pubmed/31619735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51456-7
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