Methylation content sensitive enzyme ddRAD (MCSeEd): a reference-free, whole genome profiling system to address cytosine/adenine methylation changes

Methods for investigating DNA methylation nowadays either require a reference genome and high coverage, or investigate only CG methylation. Moreover, no large-scale analysis can be performed for N(6)-methyladenosine (6 mA) at an affordable price. Here we describe the methylation content sensitive en...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Marconi, Gianpiero, Capomaccio, Stefano, Comino, Cinzia, Acquadro, Alberto, Portis, Ezio, Porceddu, Andrea, Albertini, Emidio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795852/
https://ncbi.nlm.nih.gov/pubmed/31619715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51423-2
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