IFNL3 genotype is associated with pulmonary fibrosis in patients with systemic sclerosis

Fibrosis across different organs and tissues is likely to share common pathophysiological mechanisms and pathways. Recently, a polymorphism (rs12979860) near the interferon lambda gene (IFNL3) was shown to be associated with fibrosis in liver across multiple disease etiologies. We determined whether...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Metwally, Mayada, Thabet, Khaled, Bayoumi, Ali, Nikpour, Mandana, Stevens, Wendy, Sahhar, Joanne, Zochling, Jane, Roddy, Janet, Tymms, Kathleen, Strickland, Gemma, Lester, Susan, Rischmueller, Maureen, Ngian, Gene-Siew, Walker, Jennifer, Hissaria, Pravin, Shaker, Olfat, Liddle, Christopher, Manolios, Nicholas, Beretta, Lorenzo, Proudman, Susanna, George, Jacob, Eslam, Mohammed
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795812/
https://ncbi.nlm.nih.gov/pubmed/31619697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50709-9
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