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Common architecture of Tc toxins from human and insect pathogenic bacteria

Tc toxins use a syringe-like mechanism to penetrate the membrane and translocate toxic enzymes into the host cytosol. They are composed of three components: TcA, TcB, and TcC. Low-resolution structures of TcAs from different bacteria suggest a considerable difference in their architecture and possib...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Leidreiter, F., Roderer, D., Meusch, D., Gatsogiannis, C., Benz, R., Raunser, S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795518/
https://ncbi.nlm.nih.gov/pubmed/31663026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax6497
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