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Neural Cell Adhesion Molecule 2 Promotes the Formation of Filopodia and Neurite Branching by Inducing Submembrane Increases in Ca(2+) Levels

Changes in expression of the neural cell adhesion molecule 2 (NCAM2) have been proposed to contribute to neurodevelopmental disorders in humans. The role of NCAM2 in neuronal differentiation remains, however, poorly understood. Using genetically encoded Ca(2+) reporters, we show that clustering of N...

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Publié dans:J Neurosci
Auteurs principaux: Sheng, Lifu, Leshchyns'ka, Iryna, Sytnyk, Vladimir
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795254/
https://ncbi.nlm.nih.gov/pubmed/25632147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1714-14.2015
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