Drosophila Tau Negatively Regulates Translation and Olfactory Long-Term Memory, But Facilitates Footshock Habituation and Cytoskeletal Homeostasis

Although the involvement of pathological tau in neurodegenerative dementias is indisputable, its physiological roles have remained elusive in part because its abrogation has been reported without overt phenotypes in mice and Drosophila. This was addressed using the recently described Drosophila tau(...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Papanikolopoulou, Katerina, Roussou, Ilianna G., Gouzi, Jean Y., Samiotaki, Martina, Panayotou, George, Turin, Luca, Skoulakis, Efthimios M.C.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6794924/
https://ncbi.nlm.nih.gov/pubmed/31488613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0391-19.2019
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